Review



dnam 1 fc  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    R&D Systems dnam 1 fc
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Dnam 1 Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/bio_rxiv__64898__2026__03__03__708729-181-14-15
    Average 94 stars, based on 6 article reviews
    dnam 1 fc - by Bioz Stars, 2026-10
    94/100 stars

    Images

    1) Product Images from "Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I"

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I

    Journal: bioRxiv

    doi: 10.64898/2026.03.03.708729

    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Figure Legend Snippet: (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

    Techniques Used:

    Related Articles

    Binding Assay:

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I
    Article Snippet: .. For binding assays, APC-conjugated Fc fusion protein (NKG2D-Fc (R&D Systems, Cat. No: 1299-NK) or DNAM-1-Fc (R&D Systems, Cat. No: # 666-DN) or KIR-Fc (R&D Systems, KIR2DL1-Fc (Cat. No: 1844-KR-050), KIR2DL3-Fc (Cat. No: 2014-KR-050), KIR2DS4-Fc (Cat. No: 1847-KR-050) (3.6 μg mL -1 ) was added at 25 μL per well and incubated for 30 min at 4 °C in the dark. .. For ligand detection, anti-β2M antibody (BioLegend, Cat. No:316306) or anti-CD155 (BioLegend, Cat. No: 337610) or anti-ULBP-1 (R&D Systems, Cat. No: FAB1380P) (1:75) was added at 25 μL per well.

    Incubation:

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I
    Article Snippet: .. For binding assays, APC-conjugated Fc fusion protein (NKG2D-Fc (R&D Systems, Cat. No: 1299-NK) or DNAM-1-Fc (R&D Systems, Cat. No: # 666-DN) or KIR-Fc (R&D Systems, KIR2DL1-Fc (Cat. No: 1844-KR-050), KIR2DL3-Fc (Cat. No: 2014-KR-050), KIR2DS4-Fc (Cat. No: 1847-KR-050) (3.6 μg mL -1 ) was added at 25 μL per well and incubated for 30 min at 4 °C in the dark. .. For ligand detection, anti-β2M antibody (BioLegend, Cat. No:316306) or anti-CD155 (BioLegend, Cat. No: 337610) or anti-ULBP-1 (R&D Systems, Cat. No: FAB1380P) (1:75) was added at 25 μL per well.



    Similar Products

    dnam 1 fc  (R&D Systems)
    94
    R&D Systems dnam 1 fc
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Dnam 1 Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/bio_rxiv__64898__2026__03__03__708729-181-14-15
    Average 94 stars, based on 1 article reviews
    dnam 1 fc - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    cd226  (R&D Systems)
    94
    R&D Systems cd226
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Cd226, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Mouse+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/pm41703450-104-26-33
    Average 94 stars, based on 1 article reviews
    cd226 - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    recombinant human dnam  (R&D Systems)
    94
    R&D Systems recombinant human dnam
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Recombinant Human Dnam, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/10__1097_slash_md__0000000000042844-56-2-11
    Average 94 stars, based on 1 article reviews
    recombinant human dnam - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    human cd226 fc  (R&D Systems Hematology)
    94
    R&D Systems Hematology human cd226 fc
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Human Cd226 Fc, supplied by R&D Systems Hematology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/us11919953-1139-14-19
    Average 94 stars, based on 1 article reviews
    human cd226 fc - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    666 dn  (R&D Systems Hematology)
    94
    R&D Systems Hematology 666 dn
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    666 Dn, supplied by R&D Systems Hematology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/us11919953-1139-20-19
    Average 94 stars, based on 1 article reviews
    666 dn - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    dnam‐1‐fc fusion protein  (R&D Systems)
    90
    R&D Systems dnam‐1‐fc fusion protein
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Dnam‐1‐Fc Fusion Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/human+tigit+fusion+protein++human+fc/pmc10825377-154-30-33
    Average 90 stars, based on 1 article reviews
    dnam‐1‐fc fusion protein - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    r d 4436 dn mouse dnam  (R&D Systems)
    94
    R&D Systems r d 4436 dn mouse dnam
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    R D 4436 Dn Mouse Dnam, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Mouse+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/pmc10803750__41467_2024_44861_MOESM3_ESM-84-7-6
    Average 94 stars, based on 1 article reviews
    r d 4436 dn mouse dnam - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    recombinant mouse dnam  (R&D Systems)
    94
    R&D Systems recombinant mouse dnam
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Recombinant Mouse Dnam, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnam+1+fc/Recombinant+Mouse+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/pmc10803750__41467_2024_44861_MOESM3_ESM-84-38-59
    Average 94 stars, based on 1 article reviews
    recombinant mouse dnam - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

    Journal: bioRxiv

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I

    doi: 10.64898/2026.03.03.708729

    Figure Lengend Snippet: (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

    Article Snippet: For binding assays, APC-conjugated Fc fusion protein (NKG2D-Fc (R&D Systems, Cat. No: 1299-NK) or DNAM-1-Fc (R&D Systems, Cat. No: # 666-DN) or KIR-Fc (R&D Systems, KIR2DL1-Fc (Cat. No: 1844-KR-050), KIR2DL3-Fc (Cat. No: 2014-KR-050), KIR2DS4-Fc (Cat. No: 1847-KR-050) (3.6 μg mL -1 ) was added at 25 μL per well and incubated for 30 min at 4 °C in the dark.

    Techniques: